Structure of human MPC matrix-open

Cryo-EM of pi-conjugated Peptide 2 (6 strands)

Human MPC1-2 Complex matrix-open

Cryo-EM of VEVAG Peptide 1

Cryo-ET map of the VZV capsid vertex (5-fold axis).

Human MPC1-2 Complex matrix-open (TMs weighted)

Cryo-EM of pi-conjugated Peptide 2 (9 strands)

Structure of human MPC IMS-open

Locally refined OS9-SEL1L cryo-EM map

Human MPC1-2 Complex IMS-open (TMs weighted)

BG505 MD39.3 Env gp151 MPER nanodisc in complex with 10E8, BG18 and VRC01 Fabs (1x 10E8 Fab)

Cryo-EM structure of OS9-SEL1L-HRD1 dimer

BG505 MD39.3 Env gp151 MPER nanodisc in complex with 10E8, BG18 and VRC01 Fabs (2x 10E8 Fabs)

Human MPC1-2 Complex IMS-open

BG505 MD39.3 SOSIP.664 in complex with 3BC315, BG18 and VRC01 Fabs

SPOP double donut locally refined MATH domains

SPOP double donut locally refined MATH domains

SPOP 12mer Double Donut

SPOP double donut locally refined MATH domains

Human EAAT3 with sodium bound at inward facing state

SPOP 13mer Double Donut

Human EAAT3 with compound 3e and digitonin.glyco-diosgenin bound at inward facing state

Human EAAT3 with compound 3e and cholesterol bound at inward facing state

SPOP 14mer Double Donut

E. coli 70S ribosome with unmodified tRNAPro(GGG) in the e*/E conformation on a slippery CCC-C codon

Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 2

Cryo-EM Structure of DHX36 bound to a RNA G-quadruplex derived from the cMyc G-quadruplex, Class 1

E. coli 70S ribosome with unmodified Lys-tRNAPro(GGG) in the P/P conformation on a slippery CCC-C codon

Codon sampling state obtained from Anisomycin-treated mammalian ribosomes

Codon sampling state of elongation inhibitor-treated mammalian ribosomes obtained from merged datasets

Post-decoding/Post-hydrolysis state obtained from Anisomycin-treated mammalian ribosomes

Post-decoding post-hydrolysis state obtained from merged datasets of elongation inhibitor-treated mammalian ribosomes

Mammalian ribosomes bound to Anisomycin in the rotated conformation

Anisomycin-bound mammalian ribosome with partially accommodated A-site tRNA

Mammalian ribosomes bound to Anisomycin in the nonrotated conformation

cryo-EM structure of the Nipah virus polymerase containing the connecting domain

Polyclonal immune complex of Fab from Rhesus Macaque BB798E at week 12 binding H1 HA

Structure of 16.ND.92 Fab in complex with A/Solomon Islands/3/2006(H1N1) influenza virus Hemagglutinin

Polyclonal immune complex of human subject 321-2009 Fab binding H1 HA

CryoEM structure of inducible Lysine decarboxylase from Hafnia alvei D-hydrazino-Lysine analog at 2.3 Angstrom resolution

Polyclonal immune complex of Fab from Cynomolgus Macaque T009 at week 12 binding H1 HA

Integrin alpha-v beta-3 in complex with rhodostomin

Cryo-EM structure of CpAgo_gDNA-tg_ssDNA monomeric ternary complex

cryo-EM structure of trimeric AcrB

cryo-EM structure of hexameric ArnA

Structure of FtsZ1 in complex with GMPCPP from Candidatus Odinarchaeota

arm region local refined map of Bax line

vertex region local refined map of Bax line

Cryo-EM structure of a truncated Nipah virus (Malaysia Strain) L:P complex

Light Harvesting complex 3 (LH3), B800-B820, of Rhodoblastus (Rbl.) acidophilus strain 7750

Light Harvesting complex 2 (LH2), B800-B850, of Rhodoblastus (Rbl.) acidophilus strain 7750

Structure of alpha2a adrenergic receptor in complex with Go heterotrimer, scFv16, and N-(5-methylnaphthalen-1-yl)pyridin-4-amine (compound 4905)

Ciliary tip central pair

Cryo-EM structure of Escherichia coli hibernating ribosome with RNase I mutant

Iota toxin Ib pore serine-clamp mutant(C1)

Subtomogram average of purified E. coli 70S ribosome particles

Tau-Microtubule structure in the presence of ATP

Influenza A(H5N1) Clade 2.3.4.4b in complex with head specific monoclonal antibody NVX.361.4

Structure of D10-NT amyloid fibrils

Structure of D2-NT amyloid fibrils

Structure of T61I D2-NT amyloid fibrils

Structure of R15L D10-NT amyloid fibrils

Structure of D10-NT amyloid fibrils

Structure of D10-NT amyloid fibrils

Human LARP1 bound to the 40S small ribosomal subunit

Structure of S59L D10-NT amyloid fibrils

#1664 Fab in complex with NG2 COBRA hemagglutinin

TJ5-1 Fab in complex with NG2 COBRA hemagglutinin

Cryo-EM structure of the zeaxanthin-bound light-driven proton pumping rhodopsin, NM-R1

Cryo-EM structure of the myxol-bound light-driven chloride ion-pumping rhodopsin, NM-R3

Cryo-EM structure of the myxol-bound light-driven proton pumping rhodopsin, NM-R1

Cryo-EM structure of the light-driven chloride ion-pumping rhodopsin, NM-R3

Cryo-EM structure of the human mitochondrial RNA polymerase transcription initiation complex (POLRMT/TFAM/TFB2M/DNA/RNA) with a slipped 3-mer RNA, pppGpGpA (slipped IC3)

Cryo-EM structure of the human mitochondrial RNA polymerase transcription initiation complex (POLRMT/TFB2M/DNA/RNA) without TFAM; and with a 2-mer RNA (pppGpA) and GTP poised for catalysis (pre-IC3-TFAM)

Cryo-EM structure of the human mitochondrial RNA polymerase transcription initiation complex (POLRMT/TFB2M/DNA/RNA) without TFAM; and with a slipped 3-mer RNA, pppGpGpA (slipped IC3-TFAM)

Cryo-EM structure of the human mitochondrial RNA polymerase transcription initiation complex (POLRMT/TFAM/TFB2M/DNA/RNA) with a 2-mer RNA (pppGpA) and GTP poised for catalysis (pre-IC3)

Cryo-EM structure of the human mitochondrial RNA polymerase transcription initiation complex (POLRMT/TFAM/TFB2M/DNA/RNA) with a slipped 3-mer RNA (pppGpGpA) and GTP poised for catalysis (slipped pre-IC4)

Structure of in-vivo formed alpha-synuclein fibrils purified from a M83+/- mouse brain injected with recombinant 1B fibrils

Structure of LGR4 with NB21

Cryo-EM structure of 3nv.2, a modified 426c SOSIP-based immunogen

S.aureus ClpC dodecameric resting state

S.aureus ClpC decamric resting state

RM038 Fab in complex with Apex-GT 6.2 trimer and RM20A3 Fab

RM018 Fab in complex with Apex GT 6.2 trimer and RM20A3 Fab

CryoEM structure of a broadly neutralizing anti-SARS-CoV-2 antibody 52

Structure of HKU5 spike C-terminal domain in complex with ACE2 from Pipistrellus abramus

Pre-fusion HERV-K Envelope Protein Trimer Ectodomain in complex with Kenv-6 Fab

Post-fusion HERV-K Envelope Protein in complex with Kenv-4 Fab

Focused map of Pfs230 domains 1-8 of the endogenous Pfs230-Pfs48/45 complex

Focused map of Pfs230 (domains 9-14) and Pfs48/45 of the endogenous Pfs230-Pfs48/45 complex

Composite map of the endogenous complex of Pfs230-Pfs48/45

Pre-fusion Stabilized HERV-K Envelope Trimer Ectodomain

13PF microtubule symmetry expansion

Tip CP C1 Wild Type

Tip CP C2 WT

Refinement C1 PF6-7-8

SPEF1 KO Tip CP C1

Refinement C1 PF13-1-2

Refinement C1 PF8-9-10

Refinement C1 PF2-3-4

SPEF1 KO Tip CP C2

Refinement C1 PF4-5-6

Refinement C2 PF2-3-4

Refinement C2 PF13-1-2

Refinement C1 PF10-11-12-13

Refinement C2 PF6-7-8

Refinement C2 PF8-9-10

Refinement C2 PF4-5-6

Refinement C2 PF10-11-12-13

CryoEM structure of the Azotobacter vinelandii glutamine synthetase

Cryo-EM structure of hGPR4-Gs complex in pH7.0

Cryo-EM structure of SARS-CoV-2 XBB spike protein in complex with three-nAb 8H12, 3E2 and 1C4

DCA-bound state of hPAC structure

Cryo-EM structure of CpAgo_gDNA-tg_dsDNA dimeric ternary complex

hPAC structure in the presence of MbCD

histamine-bound H2R in complex with Gs

Cryo-EM structure of CpAgo in complex with the 5'-P guide DNA.

Cryo-EM structure of CpAgo_gDNA-tg_bubble_dsDNA dimeric ternary complex

Cryo-EM structure of CpAgo_gDNA-tg_ssDNA dimeric ternary complex

Cryo-EM structure of CpAgo_gDNA-tg_bubble_dsDNA monomeric ternary complex

Cryo-EM structure of CpAgo_gDNA-tg_dsDNA monomeric ternary complex

Cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked diUb (monomeric conformation)

GPR133-Gain-miniG13 complex

Cryo-EM structure of PsCas9-sgRNA binary complex

cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked diUb (dimeric conformation)

cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked triUb (dimeric conformation)

Cryo-EM structure of PsCas9-sgRNA-dsDNA (30 nt) ternary complex

cryo-EM structure of Ufd2/Ubc4-Ub in complex with K29-linked triUb (monomeric conformation)

Cryo-EM structure of PsCas9-sgRNA-dsDNA ternary complex

CryoEM structure of human rho1 GABAA receptor in complex with GABA and neurosteroid pregnanolone

CryoEM structure of human rho1 GABAA receptor in complex with neurosteroid pregnanolone

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S28P, polymorph 1

GRP94-BiP complex, pre-loading conformation

CryoEM structure of human rho1 GABAA receptor in complex with neurosteroid THDOC

CLC7/OSTM1 complex in the absence of PIP2 lipid.

CLC7/OSTM1 complex with bound PIP2 lipid

CLC7(Y715C)/OSTM1 complex

CryoEM structure of human rho1 GABAA receptor in complex with GABA and neurosteroid THDOC

CryoEM structure of the proton-dependent antibacterial peptide transporter SbmA in complex with FabS11-1 in lipid nanodiscs at pH 5.5, inward-open state

TRPC5 in complex with photoswitch E-AzHC

Beta carbonic anhydrase CsoSCA from the Halothiobacillus neapolitanus alpha-carboxysome

CryoEM structure of the proton-dependent antibacterial peptide transporter SbmA in complex with FabS11-1 in lipid nanodiscs at pH 5.5, inward-closed state

GRP94-BiP complex, loading conformation

CryoEM structure of human rho1 GABAA receptor in complex with loreclezole

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S28P, polymorph 2

TRPC5 in complex with photoswitch Z-AzHC

CryoEM structure of human rho1 GABAA receptor in complex with GABA and loreclezole

Complex of Fap2 from Fusobacterium nucleatum with human TIGIT

Salmonella typhimurium polynucleotide phosphorylase in complex with recognition site of RNase E

Extracellular domain of the Fap2 autotransporter adhesin from Fusobacterium nucleatum ATCC23726

CryoEM structure of human rho1 GABAA receptor in complex with muscimol and neurosteroid THDOC in the primed state

CryoEM structure of human rho1 GABAA receptor in complex with muscimol in the primed state

CryoEM structure of human rho1 GABAA receptor in complex with muscimol in the intermediate state

CryoEM structure of human rho1 GABAA receptor in complex with muscimol and neurosteroid THDOC in the desensitized state

Toxoplasma gondii cytochrome bc1 complex from the respiratory supercomplex III2-IV inhibited by atovaquone and ELQ-300

Cryo-EM structure of domperidone-bound human SLC19A3 in inward-open state

Membrane-distal part of extracellular domain of the Fap2 autotransporter adhesin from Fusobacterium nucleatum ATCC23726

The NTD dimer and the interfacing LBD region of the AMPAR complex GluA3(R439G,R163I)- TARP gamma2 in the apo state.

Cryo-EM structure of human SLC45A4 in detergent

Cryo-EM structure of human SLC45A4 in lipid nanodiscs

Cryo EM structure of Nipah virus L-P polymerase complex

Ypt7 in complex with its GEF Mon1-Ccz1

Semi-active PSII dimer from native Peak4 PSII dimers

Inactive PSII dimer from native Peak4 PSII dimers

Rab23 in complex with Fuzzy-Inturned

Structure of the Ypt7 GEF complex Mon1-Ccz1 from Chaetomium Thermophilum

MmCpn in closed state wit D9 symmetry

active PSII dimer from native Peak4 PSII dimers

Closed state MmCpn under ATP/AlFx condition by subtomogram averaging

Structure of arbekacin bound Escherichia coli 70S ribosome

human Fuzzy-Inturned

Adeno-associated virus 9 variant 496-AAA-498

Adeno-associated virus 9 variant AAV9.NVG7

Tripartite complex of MmpL5-S5-AcpM from Mycolicibacterium smegmatis

CryoEM map of 4F11 and MxR Fabs bound to HMPV DS-CavEs2 preF monomer

CryoEM structure of 4F11 Fab bound to stabilized MPV-2c HMPV preF

High-resolution in situ ANDV single tetramer structure

The consensus map of MmpL5-AcpM cluster

Cluster of bipartite complex of MmpL5-AcpM from Mycolicibacterium smegmatis

Local refinement map of MmpL5-AcpM cluster part 2

Local refinement map of MmpL5-AcpM cluster part 1

Local refinement map of MmpL5-AcpM cluster part 3

Bipartite complex of MmpL5-AcpM from Mycolicibacterium smegmatis

Structure of ANDV dimer of tetramer at conformation III

Structure of the ANDV dimer of tetramer at conformation II

Structure of the ANDV dimer of tetramer at conformation I

Andes virus glycoprotein tetramer in complex with ADI-65534 Fab

Structure of CloA apo

ADI-65534-bound dimer of ANDV glycoprotein tetramers

Structure of CloA co-expressed with CloB

Structure of CloA in complex with dGTP and p3diT

Structure of CloA in complex with dGTP and dTTP

Melbournevirus Mini variant Nucleosome

Polyclonal immune complex of Fab from Cynomolgus Macaque R996 at week 12 binding H1 HA

Polyclonal immune complex of Fab from Cynomolgus Macaque 6974 at week 12 binding H1 HA

Polyclonal immune complex of human subject 321-2006 Fab binding H1 HA

Polyclonal immune complex of human subject 321-2012 Fab binding H1 HA