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Neuraminidase of A/Switzerland/9715293/2013 H3N2 in complex with CAV-F6 Fab

Electron Microscopy
2.8Å resolution
PDB entry 8yvn coloured by chain, front view.
PDB entry 8yvn coloured by chain, side view.
PDB entry 8yvn coloured by chain, top view.
Source organisms:
Assembly composition:
hetero dodecamer (preferred)
Entry contents: 3 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Neuraminidase and IG-heavy chain and IG-light kappa chain
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Multimeric state: hetero dodecamer
PDBe Complex ID: PDB-CPX-308253

Macromolecules

Neuraminidase
Chains: A, B, C, D
Length: 387 amino acids
Theoretical weight: 42.71 KDa
Source organism: Influenza A virus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A0N7G9M6 (Residues: 83-469; Coverage: 83%)
Gene name: NA
Pfam: Neuraminidase
Neuraminidase in PDB entry 8yvn, assembly 1, front view.
Neuraminidase in PDB entry 8yvn, assembly 1, side view.
Neuraminidase in PDB entry 8yvn, assembly 1, top view.
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CAV-F6 heavy chain
Chains: E, F, G, H
Length: 123 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
CAV-F6 heavy chain in PDB entry 8yvn, assembly 1, front view.
CAV-F6 heavy chain in PDB entry 8yvn, assembly 1, side view.
CAV-F6 heavy chain in PDB entry 8yvn, assembly 1, top view.
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CAV-F6 kappa chain
Chains: I, J, K, L
Length: 107 amino acids
Theoretical weight: 11.64 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
CAV-F6 kappa chain in PDB entry 8yvn, assembly 1, front view.
CAV-F6 kappa chain in PDB entry 8yvn, assembly 1, side view.
CAV-F6 kappa chain in PDB entry 8yvn, assembly 1, top view.
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