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› 8kgc

Electron Microscopy
2.54Å resolution

Cryo-EM structure of human NADK tetramer

Released:
DOI: 10.2210/pdb8kgc/pdb
PDB entry 8kgc coloured by chain, front view.
PDB entry 8kgc coloured by chain, side view.
PDB entry 8kgc coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Zhang P, Hu M, Liu Z
Related structures: EMD-37217

Function and Biology Details

Reaction catalysed: 
[NAD(+) + ATP = ADP + NADP(+) + H(+)., NAD(+) + ATP = ADP + NADP(+) + H(+)., NAD(+) + ATP = ADP + NADP(+) + H(+)., NAD(+) + ATP = ADP + NADP(+) + H(+).]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131946 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NAD kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 453 amino acids
Theoretical weight: 49.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O95544 (Residues: 1-446; Coverage: 100%)
Gene name: NADK
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.54Å
Relevant EMDB volumes: EMD-37217
Expression system: Escherichia coli

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