July, 2025
Basal MET Phosphorylation as an Indicator of Hepatocyte Dysregulation in Liver Disease
Model(s) associated with this Model of the Month: BIOMD0000001102.
Last updated by: Dr Svenja Kemmer
BioModels is a repository of mathematical models of biological and biomedical systems. It hosts a vast selection of existing literature-based physiologically and pharmaceutically relevant mechanistic models in standard formats. Our mission is to provide the systems modelling community with reproducible, high-quality, freely-accessible models published in the scientific literature. More information about using BioModels such as model submission, update, publication, or reviewers access can be found in the FAQ.
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Recently published
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GPCR Cubic Ternary Complex with G protein Cycle, Redfern-Nichols 2023
Submitter: Theo Redfern-Nichols | Published date: 2025-05-22Publication: Loss-of-function Gαs rare disease variants exert mutation-specific effects on GPCR signaling. , Science signaling (2025) -
Dual G protein Model
Submitter: Theo Redfern-Nichols | Published date: 2025-05-22Publication: Loss-of-function Gαs rare disease variants exert mutation-specific effects on GPCR signaling. , Science signaling (2025) -
Gosselin2025 - Ecoli_bioproduction_sensitive
Submitter: Millard | Published date: 2025-06-23Publication: Acetate as a metabolic booster for glucose-based bioproduction in Escherichia coli, bioRxiv preprint (Unpublished) -
Gosselin2025 - Ecoli_bioproduction_insensitive
Submitter: Millard | Published date: 2025-06-23Publication: Acetate as a metabolic booster for glucose-based bioproduction in Escherichia coli, bioRxiv preprint (Unpublished) -
Gall2023 - Agent-based model of the intestinal epithelium
Submitter: Louis Gall | Published date: 2025-05-12Publication: Homeostasis, injury and recovery dynamics at multiple scales in a self-organizing mouse intestinal crypt, eLife (2024) -
Lo2016 – IBD Response to Anti-TNFα treatment
Submitter: bastien chassagnol | Published date: 2025-05-13Publication: Inflammatory Bowel Disease: How Effective Is TNF-α Suppression?, PloS one (2016) -
Carpenter 2024 - Mechanical control of growing and homeostatic epithelia
Submitter: Logan Carpenter | Published date: 2025-04-22Publication: Mechanical control of cell proliferation patterns in growing epithelial monolayers., Biophysical journal (2024)
Recently accessed
- Novak1997 - Cell Cycle
- Talemi2014 - Arsenic toxicity and detoxification mechanisms in yeast
- Brännmark2013 - Insulin signalling in human adipocytes (normal condition)
- Haffez2017 - RAR interaction with synthetic analogues
- Stortelder1997 - Thrombin Generation Amidolytic Activity
- Hettling2011_CreatineKinase
- Bungay2003_Thrombin_Generation
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- 24/04/2025: Talk2BioModels - an AI chatbot for BioModels
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- 27/02/2021: Reproducibility in Systems Biology Modelling manuscript published
- 08/12/2020: Reproducibility
- 12/10/2020: Retirement party for the classic BioModels website
- 06/07/2020: COVID-19
- 17/06/2020: New updates for Release 5.1.9
- 03/06/2020: New updates for Release 5.1.8
- 03/06/2020: BioModels Parameters Manuscript accepted
How to cite BioModels
- Rahuman S Malik-Sheriff, Mihai Glont, Tung V N Nguyen, Krishna Tiwari, Matthew G Roberts, Ashley Xavier, Manh T Vu, Jinghao Men, Matthieu Maire, Sarubini Kananathan, Emma L Fairbanks, Johannes P Meyer, Chinmay Arankalle, Thawfeek M Varusai, Vincent Knight-Schrijver, Lu Li, Corina Dueñas-Roca, Gaurhari Dass, Sarah M Keating, Young M Park, Nicola Buso, Nicolas Rodriguez, Michael Hucka, and Henning Hermjakob
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Nucl. Acids Res. 2020
- Mihai Glont, Tung V N Nguyen, Martin Graesslin, Robert Hälke, Raza Ali, Jochen Schramm, Sarala M Wimalaratne, Varun B Kothamachu, Nicolas Rodriguez, Maciej J Swat, Jurgen Eils, Roland Eils, Camille Laibe, Rahuman S Malik-Sheriff, Vijayalakshmi Chelliah, Nicolas Le Novère, and Henning Hermjakob
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Nucl. Acids Res. 2018
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Acknowledgements
- BioModels is supported by the European Molecular Biology Laboratory, the Biotechnology and Biological Sciences Research Council (Multimod, BB/N019482/1) and the Innovative Medicines Initiative (TransQST, 116030).
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